melanoma wife: AZD6244 trial

LEARN THE ABCDEF'S OF MELANOMA!!! EARLY DETECTION IS THE KEY!

Thursday, September 17, 2009

Finally home!!

I have attached a you tube video that I would like to share...as I was waiting the past few days for Marcus, I have been searching for new christian artists on iTunes and I found Jeremy Camp's music-I quickly realized I needed to buy his album!! I LOVE the songs in this video and had to share-plus the messages and scriptures included are awesome!

So, to update you all-the brain ct and abdomen/pelvis ct came back ALL CLEAR! THANK THE LORD! The biopsy did confirm Melanoma in the lungs-so at least now we know for sure what we are dealing with. Dr. Kim is having cells from the original biopsy done last year tested for a gene mutation-V600E B-raf-if he tests positive for this mutation, they are suggesting he get into a clinical trial that includes AZD6244 and Dacarbazine. Sucky part is, this is a double blinded study-so 50% of patients will get the AZD6244 plus Dacarbazine and the other 50% will get Decarbazine and placebo :( We are not really thrilled with this option-since Dr. Kim said Dacarbazine is a standard chemo that he would offer if Marcus was 80 yrs old and in poor health-not the 1st choice for a young 35 yr old man in otherwise great health- SOOOOO, at this point we have to wait to see if he even tests positive for the gene mutation-if not, then our next option is IL-2-with a possible combo of Dacarbazine to it....

In the meantime, we are asking for more prayers-none of these options have great statistics for cure-but we believe that God will work with those numbers for us :) BUT we need your help with prayers-please don't stop-keep them coming :)

Marcus is also looking into trying to create a more alkaline based diet-there is tons of research to support the fact that cancer thrives in more acidic atmospheres, so the theory is to create a more alkaline atmosphere in your body to help fight this-so if anyone has info that may help, please email me. I am currently following the blog of another Melanoma warrior-who is currently in Mexico, at a Gerson clinic-I am praying he has good results to help us :) check him out on my blog list-he is under sMelanoma....

thank you all again for your continued prayers and support-it feels so good to be home and we know we are truly blessed to have all of you in our lives-thank you so very much!

marcus & mindy

how it all began-the "mole" story

well, just for those that don't already know-here is how this journey began. it all started with a little mole that marcus had since birth, on his thumb. in early 2007, i noticed that it had started to change-it was bigger and part of it was black and part was brown-i really didn't know much about melanoma, but i remember the way it looked-it reminded me of the mole on my niece's foot that a dr. removed when she was small, because he said if they didn't remove it, most definitely it would turn cancerous when she went through puberty. ANYWAYS, so i began nagging sweet hubby to go get it looked at. of course, he kept saying, "it's no big deal, i have had this mole since i was born-it's fine". so life went on.

well, hubby works with his hands since he is a machinist, and he bumped the mole-it bled-it grew bigger. a few months later, he bumped it at work AGAIN-it bled-it grew bigger-and now it actually started to bother him. it was sensitive.

one day out of the blue he called me from work-and asked me to make an appt. for him to go to the dr. to get the mole removed. THANK GOD! so of course i got right on that phone and made him an appt. first call to his current primary care phys. was a joke-they couldn't see him for at least another week or so because they were only seeing flu patients on fridays (the only weekday hubby has off) and didn't feel his mole was anything to fret about! well, i sure thought it was and called my primary care phys.-she had no problem seeing him on friday like he wanted!

sure enough, once he saw her, she didn't like the looks of the mole and immediately sent him to a dermatologist. and only by God's hand guiding-did she decide to NOT wait 3-6 months for a dermatolgist in beaumont to get an opening-but she sent him to a dr. in mid-county-that she didn't even know-she had just received his business card in the mail the week before-and decided since he could work hubby in so quickly-that he was the ONE!!! THANK YOU GOD!!!!

well, the next week came-marcus went to the dermatologist-wanting to get that mole removed!! to his surprise-the dr. wanted to biopsy it-he didn't like the looks of it either. (do you see a pattern here? sweet wife was on to something !) he talked the med. asst. lady into cutting as much of the mole off as she could-and she did-we later found out that she removed all the cancer from the thumb with that biopsy! one week later, we were told that the biopsy showed malignant melanoma and they sent us straight to MD Anderson in Houston!!!! talk about scary!

the medical oncologist explained that the type of cancer he had was called superficial spreading melanoma-and it liked to spread to the lymph nodes-so he suggested a partial amputation of the thumb-to make sure he got all the cancer-and a sentinal node biopsy-to see which, if any lymph nodes had cancer- Marcus wanted to save his thumb-so that is what they did. the dr. removed the margin around what was left of the mole-and took a skin graft from the side of his stomach to rebuild the thumb. this all healed very well.

they did the sentinal node biopsy and found that there was one lymph node under his arm that had cancer-it ended up having 20 cells in it-so they suggested he remove all the lypmh nodes from under his arm. he did this and all the other nodes came back CANCER FREE!!!!!!!

now they also suggested he do 4 weeks of high dose interferon to kill any cells that may have gotten loose from that node-to prevent this monster from coming back. they also want him to do 11 months of the interferon shots-but we don't know how far he will go with those. all depends on how sick they make him-and if they are anything like the high dose-he may only go 2 weeks.**MARCUS COMPLETED 4 WEEKS OF HIGH DOSE INTERFERON AND DID THE SHOTS 3/WEEK FOR ABOUT 3 MONTHS BEFORE HE STOPPED**

we later discovered that once the cancer has spread to lymph nodes closest to the mole, it is considered stage III-no one ever really told us this-we had to learn on our own.***UPDATE-8-31-09 LUNG METS WERE DISCOVERED SO MARCUS WAS UPGRADED TO STAGE IV***
***AFTER IL-2 AND SEVERAL CHEMO COMBOS, MARCUS LOST HIS BATTLE 4-1-2010. MELANOMA SUCKS!!!***

this is a brief outline of the "mole" story-hope it was easy to follow-and hope it makes everyone think twice about their moles!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! PLEASE LEARN ABOUT MELANOMA-IT IS NOT "JUST" SKIN CANCER!!!!!

melanoma wife

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LEARN THE ABCDEF'S OF MELANOMA!!! EARLY DETECTION IS THE KEY!

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Thursday, September 17, 2009

Finally home!!

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